Lyrics
(Verse 1)
There’s a game enzymes play, in the cells every day,
When a substrate finds its place, in the active site’s embrace.
But sometimes, things go wrong, inhibitions come along,
Let’s break it down, so you can ace, all those questions on the case.
(Chorus)
Competitive, Km goes high, Vmax stays the same,
Non-competitive, Km's constant, Vmax drops in the game.
Uncompetitive, both go down, what a tricky play,
Mixed inhibition, Vmax drops, Km could sway.
(Verse 2)
Competitive inhibition, they fight for the same place,
Substrate and inhibitor, they’re in a tight race.
Km goes higher, Vmax stays the same,
More substrate needed, to win the binding game.
(Chorus)
Competitive, Km goes high, Vmax stays the same,
Non-competitive, Km's constant, Vmax drops in the game.
Uncompetitive, both go down, what a tricky play,
Mixed inhibition, Vmax drops, Km could sway.
(Verse 3)
Non-competitive inhibition, binds to another site,
Changes the enzyme's shape, it’s not a fair fight.
Km stays constant, Vmax goes down,
Less product formed, it’s all around.
(Chorus)
Competitive, Km goes high, Vmax stays the same,
Non-competitive, Km's constant, Vmax drops in the game.
Uncompetitive, both go down, what a tricky play,
Mixed inhibition, Vmax drops, Km could sway.
(Verse 4)
Uncompetitive inhibition, binds only when substrate’s there,
Forms an ESI complex, it’s a tricky affair.
Km goes down, Vmax drops too,
Both decrease, what’s the enzyme to do?
(Chorus)
Competitive, Km goes high, Vmax stays the same,
Non-competitive, Km's constant, Vmax drops in the game.
Uncompetitive, both go down, what a tricky play,
Mixed inhibition, Vmax drops, Km could sway.
(Verse 5)
Mixed inhibition’s complex, binds at different sites,
Alters enzyme action, gives students some frights.
Km might rise or fall, Vmax decreases still,
Understanding these shifts, will give you the thrill.
(Chorus)
Competitive, Km goes high, Vmax stays the same,
Non-competitive, Km's constant, Vmax drops in the game.
Uncompetitive, both go down, what a tricky play,
Mixed inhibition, Vmax drops, Km could sway.
(Outro)
Now you’ve got the knowledge, to tackle enzyme quirks,
With inhibition insights, you’ll handle all the works.
Study hard, sing this tune, recall what you’ve learned,
With these enzyme kinetics, your score will be earned.
